Download E-books Biological Sequence Analysis: Probabilistic Models of Proteins and Nucleic Acids PDF

Probabilistic types have gotten more and more vital in analysing the massive volume of knowledge being produced via large-scale DNA-sequencing efforts akin to the Human Genome venture. for instance, hidden Markov versions are used for analysing organic sequences, linguistic-grammar-based probabilistic types for choosing RNA secondary constitution, and probabilistic evolutionary versions for inferring phylogenies of sequences from diverse organisms. This booklet offers a unified, updated and self-contained account, with a Bayesian slant, of such equipment, and extra more often than not to probabilistic equipment of series research. Written by means of an interdisciplinary workforce of authors, it goals to be available to molecular biologists, machine scientists, and mathematicians with out formal wisdom of the opposite fields, and whilst current the cutting-edge during this new and hugely vital box.

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