Download E-books Sequence Alignment: Methods, Models, Concepts, and Strategies PDF

The sequencing of the human genome concerned hundreds of thousands of scientists yet used fairly few instruments. this present day, acquiring sequences is less complicated, yet aligning the sequences—making convinced that sequences from one resource are effectively in comparison to these from different sources—remains a classy yet underappreciated element of comparative molecular biology. This quantity, the 1st to target this significant step in interpreting series info, is ready the perform of alignment, the methods wherein alignments are demonstrated, and extra importantly, how the results of any alignment set of rules could be interpreted. Edited by means of Michael S. Rosenberg with essays by way of the various field's best specialists, Sequence Alignment covers molecular motives, computational advances, methods for assessing alignment caliber, and philosophical underpinnings of the algorithms themselves.

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